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Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model

BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive epithelial tumor which shows very poor prognosis and high rate of recurrence, representing an urgent problem for public healthcare. MicroRNAs (miRNAs/miRs) are a class of small, non-coding RNAs that attract great attention because of their...

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Detalles Bibliográficos
Autores principales: Del Vecchio, Filippo, Gallo, Francesco, Di Marco, Antinisca, Mastroiaco, Valentina, Caianiello, Pasquale, Zazzeroni, Francesca, Alesse, Edoardo, Tessitore, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676132/
https://www.ncbi.nlm.nih.gov/pubmed/26652480
http://dx.doi.org/10.1186/s12859-015-0836-1