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Penalized weighted low-rank approximation for robust recovery of recurrent copy number variations

BACKGROUND: Copy number variation (CNV) analysis has become one of the most important research areas for understanding complex disease. With increasing resolution of array-based comparative genomic hybridization (aCGH) arrays, more and more raw copy number data are collected for multiple arrays. It...

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Detalles Bibliográficos
Autor principal: Gao, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676147/
https://www.ncbi.nlm.nih.gov/pubmed/26652207
http://dx.doi.org/10.1186/s12859-015-0835-2