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Randomized trial of primaquine hypnozoitocidal efficacy when administered with artemisinin-combined blood schizontocides for radical cure of Plasmodium vivax in Indonesia

BACKGROUND: Safety and efficacy of primaquine against repeated attacks of Plasmodium vivax depends upon co-administered blood schizontocidal therapy in radical cure. We assessed primaquine (PQ) as hypnozoitocide when administered with dihydroartemisinin-piperaquine (Eurartesim®, DHA-PP) or artesunat...

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Detalles Bibliográficos
Autores principales: Nelwan, Erni J., Ekawati, Lenny L., Tjahjono, Bagus, Setiabudy, Rianto, Sutanto, Inge, Chand, Krisin, Ekasari, Tyas, Djoko, Dwi, Basri, Hasan, Taylor, W. Robert, Duparc, Stephan, Subekti, Decy, Elyazar, Iqbal, Noviyanti, Rintis, Sudoyo, Herawati, Baird, J. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676167/
https://www.ncbi.nlm.nih.gov/pubmed/26654101
http://dx.doi.org/10.1186/s12916-015-0535-9