Parameterizing sequence alignment with an explicit evolutionary model

BACKGROUND: Inference of sequence homology is inherently an evolutionary question, dependent upon evolutionary divergence. However, the insertion and deletion penalties in the most widely used methods for inferring homology by sequence alignment, including BLAST and profile hidden Markov models (pro...

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Detalles Bibliográficos
Autores principales: Rivas, Elena, Eddy, Sean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676179/
https://www.ncbi.nlm.nih.gov/pubmed/26652060
http://dx.doi.org/10.1186/s12859-015-0832-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676179/
https://www.ncbi.nlm.nih.gov/pubmed/26652060
http://dx.doi.org/10.1186/s12859-015-0832-5

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