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IS26-Mediated Precise Excision of the IS26-aphA1a Translocatable Unit

We recently showed that, in the absence of RecA-dependent homologous recombination, the Tnp26 transposase catalyzes cointegrate formation via a conservative reaction between two preexisting IS26, and this is strongly preferred over replicative transposition to a new site. Here, the reverse reaction...

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Detalles Bibliográficos
Autores principales: Harmer, Christopher J., Hall, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676283/
https://www.ncbi.nlm.nih.gov/pubmed/26646012
http://dx.doi.org/10.1128/mBio.01866-15