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Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome
The Reelin signaling pathway is implicated in processes controlling synaptic plasticity and hippocampus-dependent learning and memory. A single direct in vivo application of Reelin enhances long-term potentiation, increases dendritic spine density and improves associative and spatial learning and me...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676289/ https://www.ncbi.nlm.nih.gov/pubmed/25864922 http://dx.doi.org/10.1111/ejn.12893 |