Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome

The Reelin signaling pathway is implicated in processes controlling synaptic plasticity and hippocampus-dependent learning and memory. A single direct in vivo application of Reelin enhances long-term potentiation, increases dendritic spine density and improves associative and spatial learning and me...

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Detalles Bibliográficos
Autores principales: Hethorn, Whitney R, Ciarlone, Stephanie L, Filonova, Irina, Rogers, Justin T, Aguirre, Daniela, Ramirez, Raquel A, Grieco, Joseph C, Peters, Melinda M, Gulick, Danielle, Anderson, Anne E, L Banko, Jessica, Lussier, April L, Weeber, Edwin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Clinical and Translational Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676289/
https://www.ncbi.nlm.nih.gov/pubmed/25864922
http://dx.doi.org/10.1111/ejn.12893

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