Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

[Image: see text] While a conserved tyrosine (Tyr) is found in oxidases, the roles of phenol ring pK(a) and reduction potential in O(2) reduction have not been defined despite many years of research on numerous oxidases and their models. These issues represent major challenges in our understanding o...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Lv, Xiaoxuan, Li, Jiasong, Zhou, Qing, Cui, Chang, Hosseinzadeh, Parisa, Mukherjee, Arnab, Nilges, Mark J., Wang, Jiangyun, Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676419/
https://www.ncbi.nlm.nih.gov/pubmed/25672571
http://dx.doi.org/10.1021/ja5109936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676419/
https://www.ncbi.nlm.nih.gov/pubmed/25672571
http://dx.doi.org/10.1021/ja5109936

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