Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition

Although lung cancers with activating mutations in the epidermal growth factor receptor (EGFR) are highly sensitive to selective EGFR tyrosine kinase inhibitors (TKIs), these tumors invariably develop acquired drug resistance. Host stromal cells have been found to have a considerable effect on the s...

Descripción completa

Detalles Bibliográficos
Autores principales: Choe, Chungyoul, Shin, Yong-Sung, Kim, Changhoon, Choi, So-Jung, Lee, Jinseon, Kim, So Young, Cho, Yong Beom, Kim, Jhingook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676617/
https://www.ncbi.nlm.nih.gov/pubmed/26676152
http://dx.doi.org/10.2147/OTT.S89659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676617/
https://www.ncbi.nlm.nih.gov/pubmed/26676152
http://dx.doi.org/10.2147/OTT.S89659

Ejemplares similares