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Medicarpin, a Natural Pterocarpan, Heals Cortical Bone Defect by Activation of Notch and Wnt Canonical Signaling Pathways

We evaluated the bone regeneration and healing effect of Medicarpin (med) in cortical bone defect model that heals by intramembranous ossification. For the study, female Sprague–Dawley rats were ovariectomized and rendered osteopenic. A drill hole injury was generated in mid femoral bones of all the...

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Detalles Bibliográficos
Autores principales: Dixit, Manisha, Raghuvanshi, Ashutosh, Gupta, Chandra Prakash, Kureel, Jyoti, Mansoori, Mohd Nizam, Shukla, Priyanka, John, Aijaz A., Singh, Kavita, Purohit, Dipak, Awasthi, Pallavi, Singh, Divya, Goel, Atul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676632/
https://www.ncbi.nlm.nih.gov/pubmed/26657206
http://dx.doi.org/10.1371/journal.pone.0144541