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Aptamers Binding to c-Met Inhibiting Tumor Cell Migration
The human receptor tyrosine kinase c-Met plays an important role in the control of critical cellular processes. Since c-Met is frequently over expressed or deregulated in human malignancies, blocking its activation is of special interest for therapy. In normal conditions, the c-Met receptor is activ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676636/ https://www.ncbi.nlm.nih.gov/pubmed/26658271 http://dx.doi.org/10.1371/journal.pone.0142412 |