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A Novel Interaction between TFII-I and Mdm2 with a Negative Effect on TFII-I Transcriptional Activity

Williams-Beuren syndrome-associated transcription factor TFII-I plays a critical regulatory role in bone and neural tissue development and in immunity, in part by regulating cell proliferation in response to mitogens. Mdm2, a cellular oncogene responsible for the loss of p53 tumor suppressor activit...

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Detalles Bibliográficos
Autores principales: Cetkovská, Kateřina, Šustová, Hana, Kosztyu, Pavlína, Uldrijan, Stjepan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676684/
https://www.ncbi.nlm.nih.gov/pubmed/26656605
http://dx.doi.org/10.1371/journal.pone.0144753