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A Novel Interaction between TFII-I and Mdm2 with a Negative Effect on TFII-I Transcriptional Activity
Williams-Beuren syndrome-associated transcription factor TFII-I plays a critical regulatory role in bone and neural tissue development and in immunity, in part by regulating cell proliferation in response to mitogens. Mdm2, a cellular oncogene responsible for the loss of p53 tumor suppressor activit...
Autores principales: | Cetkovská, Kateřina, Šustová, Hana, Kosztyu, Pavlína, Uldrijan, Stjepan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676684/ https://www.ncbi.nlm.nih.gov/pubmed/26656605 http://dx.doi.org/10.1371/journal.pone.0144753 |
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