Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor

The melanocortin 1 receptor gene (MC1R) expressed in melanocytes is a major determinant of skin pigmentation. It encodes a Gs protein-coupled receptor activated by α-melanocyte stimulating hormone (αMSH). Human MC1R has an inefficient poly(A) site allowing intergenic splicing with its downstream nei...

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Detalles Bibliográficos
Autores principales: Herraiz, Cecilia, Olivares, Conchi, Castejón-Griñán, Maria, Abrisqueta, Marta, Jiménez-Cervantes, Celia, García-Borrón, José Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676704/
https://www.ncbi.nlm.nih.gov/pubmed/26657157
http://dx.doi.org/10.1371/journal.pone.0144757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676704/
https://www.ncbi.nlm.nih.gov/pubmed/26657157
http://dx.doi.org/10.1371/journal.pone.0144757

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