CYP2D6 Metabolism in Frail Elderly Compared to Non-Frail Elderly: A Pilot Feasibility Study

BACKGROUND: Frailty is a clinical phenotype that is associated with adverse health outcomes. Since frail patients may be more prone for adverse drug events and about 15–20 % of commonly prescribed drugs are metabolized by CYP2D6, we hypothesized that CYP2D6 metabolism is decreased in frail patients...

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Detalles Bibliográficos
Autores principales: Opdam, F. L., Modak, A. S., Mooijaart, S. P., Louwerens, M., de Waal, M. W. M., Gelderblom, H., Guchelaar, H.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676788/
https://www.ncbi.nlm.nih.gov/pubmed/26597400
http://dx.doi.org/10.1007/s40266-015-0319-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676788/
https://www.ncbi.nlm.nih.gov/pubmed/26597400
http://dx.doi.org/10.1007/s40266-015-0319-0

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