Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague–Dawley rats

BACKGROUND: In addition to its classical effects on opioid receptors, morphine can activate glia and stimulate the production of pro-inflammatory immune molecules which in turn counteract the analgesic properties of morphine. We hypothesized that decreased morphine analgesia in females may be the re...

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Detalles Bibliográficos
Autores principales: Posillico, Caitlin K., Terasaki, Laurne S., Bilbo, Staci D., Schwarz, Jaclyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676821/
https://www.ncbi.nlm.nih.gov/pubmed/26693004
http://dx.doi.org/10.1186/s13293-015-0049-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676821/
https://www.ncbi.nlm.nih.gov/pubmed/26693004
http://dx.doi.org/10.1186/s13293-015-0049-3

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