Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy

BACKGROUND: Several studies in animal models demonstrated that obligate and facultative anaerobic bacteria of the genera Bifidobacterium, Salmonella, or Clostridium specifically colonize solid tumors. Consequently, these and other bacteria are discussed as live vectors to deliver therapeutic genes t...

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Detalles Bibliográficos
Autores principales: Osswald, Annika, Sun, Zhongke, Grimm, Verena, Ampem, Grace, Riegel, Karin, Westendorf, Astrid M., Sommergruber, Wolfgang, Otte, Kerstin, Dürre, Peter, Riedel, Christian U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Technical Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676896/
https://www.ncbi.nlm.nih.gov/pubmed/26655167
http://dx.doi.org/10.1186/s12934-015-0383-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676896/
https://www.ncbi.nlm.nih.gov/pubmed/26655167
http://dx.doi.org/10.1186/s12934-015-0383-5

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