Cargando…
Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy
BACKGROUND: Several studies in animal models demonstrated that obligate and facultative anaerobic bacteria of the genera Bifidobacterium, Salmonella, or Clostridium specifically colonize solid tumors. Consequently, these and other bacteria are discussed as live vectors to deliver therapeutic genes t...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676896/ https://www.ncbi.nlm.nih.gov/pubmed/26655167 http://dx.doi.org/10.1186/s12934-015-0383-5 |