Cargando…

Cold Denaturation Unveiled: Molecular Mechanism of the Asymmetric Unfolding of Yeast Frataxin

What is the mechanism that determines the denaturation of proteins at low temperatures, which is, by now, recognized as a fundamental property of all proteins? We present experimental evidence that clarifies the role of specific interactions that favor the entrance of water into the hydrophobic core...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanfelice, Domenico, Morandi, Edoardo, Pastore, Annalisa, Niccolai, Neri, Temussi, Piero Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676917/
https://www.ncbi.nlm.nih.gov/pubmed/26426928
http://dx.doi.org/10.1002/cphc.201500765