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Dopamine D2 Receptor Is Involved in Alleviation of Type II Collagen-Induced Arthritis in Mice

Human and murine lymphocytes express dopamine (DA) D2-like receptors including DRD2, DRD3, and DRD4. However, their roles in rheumatoid arthritis (RA) are less clear. Here we showed that lymphocyte DRD2 activation alleviates both imbalance of T-helper (Th)17/T-regulatory (Treg) cells and inflamed sy...

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Detalles Bibliográficos
Autores principales: Lu, Jian-Hua, Liu, Yi-Qian, Deng, Qiao-Wen, Peng, Yu-Ping, Qiu, Yi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677027/
https://www.ncbi.nlm.nih.gov/pubmed/26693483
http://dx.doi.org/10.1155/2015/496759