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Inhibition of ACE Retards Tau Hyperphosphorylation and Signs of Neuronal Degeneration in Aged Rats Subjected to Chronic Mild Stress

With increasing life expectancy, Alzheimer's disease (AD) and other types of age-associated dementia are on the rise worldwide. Treatment approaches for dementia are insufficient and novel therapies are not readily available. In this context repurposing of established drugs appears attractive....

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Detalles Bibliográficos
Autores principales: AbdAlla, Said, el Hakim, Ahmed, Abdelbaset, Ahmed, Elfaramawy, Yasser, Quitterer, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677170/
https://www.ncbi.nlm.nih.gov/pubmed/26697495
http://dx.doi.org/10.1155/2015/917156