Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis

Objective. To investigate the effect and mechanism of the exenatide on diabetic cardiomyopathy. Methods. Rats were divided into control group, diabetes group (D), diabetes treated with insulin (DI) group, and diabetes treat with exenatide (DE) group. We detected apoptosis rate by TUNEL, the adiponec...

Descripción completa

Detalles Bibliográficos
Autores principales: XiaoTian, Lei, QiNan, Wu, XiaGuang, Gan, WuQuan, Deng, Bing, Chen, ZiWen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677202/
https://www.ncbi.nlm.nih.gov/pubmed/26759813
http://dx.doi.org/10.1155/2016/4219735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677202/
https://www.ncbi.nlm.nih.gov/pubmed/26759813
http://dx.doi.org/10.1155/2016/4219735

Ejemplares similares