The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance

The transcription factor, nuclear factor erythroid 2 p45-related factor 2 (Nrf2), acts as a sensor of oxidative or electrophilic stresses and plays a pivotal role in redox homeostasis. Oxidative or electrophilic agents cause a conformational change in the Nrf2 inhibitory protein Keap1 inducing the n...

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Detalles Bibliográficos
Autores principales: Furfaro, A. L., Traverso, N., Domenicotti, C., Piras, S., Moretta, L., Marinari, U. M., Pronzato, M. A., Nitti, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677237/
https://www.ncbi.nlm.nih.gov/pubmed/26697129
http://dx.doi.org/10.1155/2016/1958174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677237/
https://www.ncbi.nlm.nih.gov/pubmed/26697129
http://dx.doi.org/10.1155/2016/1958174

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