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Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche

The gastrointestinal epithelium is characterized by a high turnover of cells and intestinal stem cells predominantly reside at the bottom of crypts and their progeny serve to maintain normal intestinal homeostasis. Accumulating evidence demonstrates the pivotal role of a niche surrounding intestinal...

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Detalles Bibliográficos
Autores principales: Pastuła, Agnieszka, Middelhoff, Moritz, Brandtner, Anna, Tobiasch, Moritz, Höhl, Bettina, Nuber, Andreas H., Demir, Ihsan Ekin, Neupert, Steffi, Kollmann, Patrick, Mazzuoli-Weber, Gemma, Quante, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677245/
https://www.ncbi.nlm.nih.gov/pubmed/26697073
http://dx.doi.org/10.1155/2016/3710836