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Differentiation of Bone Marrow Mesenchymal Stem Cells to Cardiomyocyte-Like Cells Is Regulated by the Combined Low Dose Treatment of Transforming Growth Factor-β1 and 5-Azacytidine

Bone marrow mesenchymal stem cells (BMMSCs) are used in cardiac tissue engineering for the regeneration of diseased hearts. We examined the differentiation of rat BMMSCs into cardiomyocyte-like cells when induced with a combined low dose treatment of transforming growth factor-β1 (TGF-β1) and 5-azac...

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Detalles Bibliográficos
Autores principales: Shi, Shutian, Wu, Xingxin, Wang, Xiao, Hao, Wen, Miao, Huangtai, Zhen, Lei, Nie, Shaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677250/
https://www.ncbi.nlm.nih.gov/pubmed/26697074
http://dx.doi.org/10.1155/2016/3816256