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Targeting Glia with N-Acetylcysteine Modulates Brain Glutamate and Behaviors Relevant to Neurodevelopmental Disorders in C57BL/6J Mice

An imbalance between excitatory (E) glutamate and inhibitory (I) GABA transmission may underlie neurodevelopmental conditions such as autism spectrum disorder (ASD) and schizophrenia. This may be direct, through alterations in synaptic genes, but there is increasing evidence for the importance of in...

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Detalles Bibliográficos
Autores principales: Durieux, Alice M. S., Fernandes, Cathy, Murphy, Declan, Labouesse, Marie Anais, Giovanoli, Sandra, Meyer, Urs, Li, Qi, So, Po-Wah, McAlonan, Grainne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677305/
https://www.ncbi.nlm.nih.gov/pubmed/26696857
http://dx.doi.org/10.3389/fnbeh.2015.00343