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Disassembly of the self-assembled, double-ring structure of proteasome α7 homo-tetradecamer by α6

The 20S core particle of the eukaryotic proteasome is composed of two α- and two β-rings, each of which is a hetero-heptamer composed of seven homologous but distinct subunits. Although formation of the eukaryotic proteasome is a highly ordered process assisted by assembly chaperones, α7, an α-ring...

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Detalles Bibliográficos
Autores principales: Ishii, Kentaro, Noda, Masanori, Yagi, Hirokazu, Thammaporn, Ratsupa, Seetaha, Supaporn, Satoh, Tadashi, Kato, Koichi, Uchiyama, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677347/
https://www.ncbi.nlm.nih.gov/pubmed/26657688
http://dx.doi.org/10.1038/srep18167