Akbu-LAAO exhibits potent anti-tumor activity to HepG2 cells partially through produced H(2)O(2) via TGF-β signal pathway

Previously, we characterized the biological properties of Akbu-LAAO, a novel L-amino acid oxidase from Agkistrodon blomhoffii ussurensis snake venom (SV). Current work investigated its in vitro anti-tumor activity and underlying mechanism on HepG2 cells. Akbu-LAAO inhibited HepG2 growth time and dos...

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Detalles Bibliográficos
Autores principales: Guo, Chunmei, Liu, Shuqing, Dong, Panpan, Zhao, Dongting, Wang, Chengyi, Tao, Zhiwei, Sun, Ming-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677388/
https://www.ncbi.nlm.nih.gov/pubmed/26655928
http://dx.doi.org/10.1038/srep18215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677388/
https://www.ncbi.nlm.nih.gov/pubmed/26655928
http://dx.doi.org/10.1038/srep18215

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