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pH-responsive glycol chitosan-cross-linked carboxymethyl-β-cyclodextrin nanoparticles for controlled release of anticancer drugs

Carboxymethyl-β-cyclodextrin (CMβ-CD)-modified glycol chitosan (GCS) nanoparticles (GCS-CMβ-CD NPs) were synthesized, and their pH-sensitive drug-release properties were investigated. GCS-CMβ-CD NPs could encapsulate doxorubicin hydrochloride (DOX), and the encapsulation efficiency and loading capac...

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Detalles Bibliográficos
Autores principales: Wang, Yiwen, Qin, Fei, Tan, Haina, Zhang, Yan, Jiang, Miao, Lu, Mei, Yao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677651/
https://www.ncbi.nlm.nih.gov/pubmed/26677325
http://dx.doi.org/10.2147/IJN.S91906