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Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Muscarinic M1 acetylcholine receptors (M1Rs) are highly expressed in the hippocampus, and their inhibition or ablation disrupts the encoding of spatial memory. It has been hypothesized that the principal mechanism by which M1Rs influence spatial memory is by the regulation of hippocampal synaptic pl...

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Detalles Bibliográficos
Autores principales: Dennis, Siobhan H., Pasqui, Francesca, Colvin, Ellen M., Sanger, Helen, Mogg, Adrian J., Felder, Christian C., Broad, Lisa M., Fitzjohn, Steve M., Isaac, John T.R., Mellor, Jack R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677984/
https://www.ncbi.nlm.nih.gov/pubmed/26472558
http://dx.doi.org/10.1093/cercor/bhv227