Cargando…

Nogo Receptor Signaling Restricts Adult Neural Plasticity by Limiting Synaptic AMPA Receptor Delivery

Experience-dependent plasticity is limited in the adult brain, and its molecular and cellular mechanisms are poorly understood. Removal of the myelin-inhibiting signaling protein, Nogo receptor (NgR1), restores adult neural plasticity. Here we found that, in NgR1-deficient mice, whisker experience-d...

Descripción completa

Detalles Bibliográficos
Autores principales: Jitsuki, Susumu, Nakajima, Waki, Takemoto, Kiwamu, Sano, Akane, Tada, Hirobumi, Takahashi-Jitsuki, Aoi, Takahashi, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677985/
https://www.ncbi.nlm.nih.gov/pubmed/26472557
http://dx.doi.org/10.1093/cercor/bhv232