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Oligomerization and endocytosis of Hedgehog is necessary for its efficient exovesicular secretion
Hedgehog (Hh) is a secreted morphogen involved in both short- and long-range signaling necessary for tissue patterning during development. It is unclear how this dually lipidated protein is transported over a long range in the aqueous milieu of interstitial spaces. We previously showed that the long...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678025/ https://www.ncbi.nlm.nih.gov/pubmed/26490120 http://dx.doi.org/10.1091/mbc.E15-09-0671 |