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Antiangiogenic and Neurogenic Activities of Sleeping Beauty-Mediated PEDF-Transfected RPE Cells In Vitro and In Vivo

Pigment epithelium-derived factor (PEDF) is a potent multifunctional protein that inhibits angiogenesis and has neurogenic and neuroprotective properties. Since the wet form of age-related macular degeneration is characterized by choroidal neovascularization (CNV), PEDF would be an ideal candidate t...

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Detalles Bibliográficos
Autores principales: Johnen, Sandra, Djalali-Talab, Yassin, Kazanskaya, Olga, Möller, Theresa, Harmening, Nina, Kropp, Martina, Izsvák, Zsuzsanna, Walter, Peter, Thumann, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678073/
https://www.ncbi.nlm.nih.gov/pubmed/26697494
http://dx.doi.org/10.1155/2015/863845