How many TCR clonotypes does a body maintain?

We consider the lifetime of a T cell clonotype, the set of T cells with the same T cell receptor, from its thymic origin to its extinction in a multiclonal repertoire. Using published estimates of total cell numbers and thymic production rates, we calculate the mean number of cells per TCR clonotype...

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Detalles Bibliográficos
Autores principales: Lythe, Grant, Callard, Robin E., Hoare, Rollo L., Molina-París, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678146/
https://www.ncbi.nlm.nih.gov/pubmed/26546971
http://dx.doi.org/10.1016/j.jtbi.2015.10.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678146/
https://www.ncbi.nlm.nih.gov/pubmed/26546971
http://dx.doi.org/10.1016/j.jtbi.2015.10.016

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