Cargando…

Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells

There are numerous studies that demonstrate the anti-neoplastic activity of phosphatidylinositol 3-kinase (PI3K) inhibitors and the mechanisms of inducing autophagy in cancer cells. The new anticancer drug puquitinib mesylate (XC-302) is a molecular-targeted drug, which suppresses the activity of PI...

Descripción completa

Detalles Bibliográficos
Autores principales: WANG, KE-FENG, YANG, HANG, JIANG, WEN-QI, LI, SU, CAI, YU-CHEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678157/
https://www.ncbi.nlm.nih.gov/pubmed/26499488
http://dx.doi.org/10.3892/ijmm.2015.2378