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Insulin sensitivity of muscle protein metabolism is altered in patients with chronic kidney disease and metabolic acidosis

An emergent hypothesis is that a resistance to the anabolic drive by insulin may contribute to loss of strength and muscle mass in patients with chronic kidney disease (CKD). We tested whether insulin resistance extends to protein metabolism using the forearm perfusion method with arterial insulin i...

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Detalles Bibliográficos
Autores principales: Garibotto, Giacomo, Sofia, Antonella, Russo, Rodolfo, Paoletti, Ernesto, Bonanni, Alice, Parodi, Emanuele L, Viazzi, Francesca, Verzola, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678169/
https://www.ncbi.nlm.nih.gov/pubmed/26308671
http://dx.doi.org/10.1038/ki.2015.247