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Insulin sensitivity of muscle protein metabolism is altered in patients with chronic kidney disease and metabolic acidosis
An emergent hypothesis is that a resistance to the anabolic drive by insulin may contribute to loss of strength and muscle mass in patients with chronic kidney disease (CKD). We tested whether insulin resistance extends to protein metabolism using the forearm perfusion method with arterial insulin i...
Autores principales: | Garibotto, Giacomo, Sofia, Antonella, Russo, Rodolfo, Paoletti, Ernesto, Bonanni, Alice, Parodi, Emanuele L, Viazzi, Francesca, Verzola, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678169/ https://www.ncbi.nlm.nih.gov/pubmed/26308671 http://dx.doi.org/10.1038/ki.2015.247 |
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