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The effect of PrP(Sc) accumulation on inflammatory gene expression within sheep peripheral lymphoid tissue

Accumulation of the misfolded prion protein, PrP(Sc) in the central nervous system (CNS) is strongly linked to progressive neurodegenerative disease. For many transmissible spongiform encephalopathies (TSEs), peripheral lymphoid tissue is an important site of PrP(Sc) amplification but without gross...

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Detalles Bibliográficos
Autores principales: Gossner, Anton G., Hopkins, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Pub. Co 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678288/
https://www.ncbi.nlm.nih.gov/pubmed/26507419
http://dx.doi.org/10.1016/j.vetmic.2015.10.013