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The effect of PrP(Sc) accumulation on inflammatory gene expression within sheep peripheral lymphoid tissue
Accumulation of the misfolded prion protein, PrP(Sc) in the central nervous system (CNS) is strongly linked to progressive neurodegenerative disease. For many transmissible spongiform encephalopathies (TSEs), peripheral lymphoid tissue is an important site of PrP(Sc) amplification but without gross...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Pub. Co
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678288/ https://www.ncbi.nlm.nih.gov/pubmed/26507419 http://dx.doi.org/10.1016/j.vetmic.2015.10.013 |