Cargando…

The effect of PrP(Sc) accumulation on inflammatory gene expression within sheep peripheral lymphoid tissue

Accumulation of the misfolded prion protein, PrP(Sc) in the central nervous system (CNS) is strongly linked to progressive neurodegenerative disease. For many transmissible spongiform encephalopathies (TSEs), peripheral lymphoid tissue is an important site of PrP(Sc) amplification but without gross...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gossner, Anton G., Hopkins, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Scientific Pub. Co 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678288/ https://www.ncbi.nlm.nih.gov/pubmed/26507419 http://dx.doi.org/10.1016/j.vetmic.2015.10.013

Ejemplares similares

Transcriptome analysis of CNS immediately before and after the detection of PrP(Sc) in SSBP/1 sheep scrapie
por: Gossner, Anton G., et al.
Publicado: (2014)

PrP Expression, PrP(Sc) Accumulation and Innervation of Splenic Compartments in Sheep Experimentally Infected with Scrapie
por: Sørby, Randi, et al.
Publicado: (2009)

Distribution of Peripheral PrP(Sc) in Sheep with Naturally Acquired Scrapie
por: Garza, María Carmen, et al.
Publicado: (2014)

Accumulation profiles of PrP(Sc) in hemal nodes of naturally and experimentally scrapie-infected sheep
por: Dassanayake, Rohana P, et al.
Publicado: (2013)

The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)

Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions
por: Miyazawa, Kohtaro, et al.
Publicado: (2015)

PK-sensitive PrP(Sc) Is Infectious and Shares Basic Structural Features with PK-resistant PrP(Sc)
por: Sajnani, Gustavo, et al.
Publicado: (2012)

PrP(Sc )spreading patterns in the brain of sheep linked to different prion types
por: Wemheuer, Wiebke M, et al.
Publicado: (2011)

Sparse PrP(Sc )accumulation in the placentas of goats with naturally acquired scrapie
por: O'Rourke, Katherine I, et al.
Publicado: (2011)

Recombinant PrP(Sc) shares structural features with brain-derived PrP(Sc): Insights from limited proteolysis
por: Sevillano, Alejandro M., et al.
Publicado: (2018)

Inflammatory response of microglia to prions is controlled by sialylation of PrP(Sc)
por: Srivastava, Saurabh, et al.
Publicado: (2018)

Heterogeneity of Abnormal Prion Protein (PrP(Sc)) in Murine Scrapie Prions Determined by PrP(Sc)-Specific Monoclonal Antibodies
por: USHIKI-KAKU, Yuko, et al.
Publicado: (2013)

Detection and Localisation of PrP(Sc) in the Liver of Sheep Infected with Scrapie and Bovine Spongiform Encephalopathy
por: Everest, Sally J., et al.
Publicado: (2011)

Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)
por: McCarthy, James M., et al.
Publicado: (2013)

Species and Strain Glycosylation Patterns of PrP(Sc)
por: Xanthopoulos, Konstantinos, et al.
Publicado: (2009)

Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrP(Sc) and Enable Ultrasensitive Detection of Bovine PrP(Sc)
por: Murayama, Yuichi, et al.
Publicado: (2010)

PrP(Sc )detection in formalin-fixed paraffin-embedded tissue by ELISA
por: Nicholson, Eric M, et al.
Publicado: (2011)

Accumulation of Pathological Prion Protein PrP(Sc) in the Skin of Animals with Experimental and Natural Scrapie
por: Thomzig, Achim, et al.
Publicado: (2007)

PrP(Sc) formation and clearance as determinants of prion tropism
por: Shikiya, Ronald A., et al.
Publicado: (2017)

Modeling PrP(Sc) Generation Through Deformed Templating
por: Spagnolli, Giovanni, et al.
Publicado: (2020)

Assessment of Strain-Specific PrP(Sc) Elongation Rates Revealed a Transformation of PrP(Sc) Properties during Protein Misfolding Cyclic Amplification
por: Gonzalez-Montalban, Nuria, et al.
Publicado: (2012)

Small Protease Sensitive Oligomers of PrP(Sc) in Distinct Human Prions Determine Conversion Rate of PrP(C)
por: Kim, Chae, et al.
Publicado: (2012)

Glimepiride Reduces the Expression of PrP(C), Prevents PrP(Sc) Formation and Protects against Prion Mediated Neurotoxicity
por: Bate, Clive, et al.
Publicado: (2009)

A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines
por: Jones, Daryl Rhys, et al.
Publicado: (2010)

Identifying critical sites of PrP(c)-PrP(Sc) interaction in prion-infected cells by dominant-negative inhibition
por: Taguchi, Yuzuru, et al.
Publicado: (2013)

Exploration of the Main Sites for the Transformation of Normal Prion Protein (PrP(C)) into Pathogenic Prion Protein (PrP(sc))
por: Liu, Xi-Lin, et al.
Publicado: (2017)

How do PrP(Sc) Prions Spread between Host Species, and within Hosts?
por: Mabbott, Neil A.
Publicado: (2017)

Predicting the consequences of selecting on PrP genotypes on PrP frequencies, performance and inbreeding in commercial meat sheep populations
por: Man, Wing-Young N, et al.
Publicado: (2007)

Enhancement of binding avidity by bivalent binding enables PrP(Sc)-specific detection by anti-PrP monoclonal antibody 132
por: Suzuki, Akio, et al.
Publicado: (2019)

The Octarepeat Region of the Prion Protein Is Conformationally Altered in PrP(Sc)
por: Yam, Alice Y., et al.
Publicado: (2010)

PrP(Sc)-Specific Antibodies with the Ability to Immunodetect Prion Oligomers
por: Tayebi, Mourad, et al.
Publicado: (2011)

Inhibition of cholesterol recycling impairs cellular PrP(Sc) propagation
por: Gilch, Sabine, et al.
Publicado: (2009)

Re-Assessment of PrP(Sc) Distribution in Sporadic and Variant CJD
por: Rubenstein, Richard, et al.
Publicado: (2013)

The prion 2018 round tables (I): the structure of PrP(Sc)
por: Baskakov, Ilia V., et al.
Publicado: (2019)

Quaternary Structure Changes for PrP(Sc) Predate PrP(C) Downregulation and Neuronal Death During Progression of Experimental Scrapie Disease
por: Eskandari-Sedighi, Ghazaleh, et al.
Publicado: (2020)

PrP(C) expression and prion seeding activity in the alimentary tract and lymphoid tissue of deer
por: Davenport, Kristen A., et al.
Publicado: (2017)

Detection of PrP(Sc) in lung and mammary gland is favored by the presence of Visna/maedi virus lesions in naturally coinfected sheep
por: Salazar, Eider, et al.
Publicado: (2010)

Heterogeneity of the Abnormal Prion Protein (PrP(Sc)) of the Chandler Scrapie Strain
por: Kasai, Kazuo, et al.
Publicado: (2013)

Early existence and biochemical evolution characterise acutely synaptotoxic PrP(Sc)
por: Foliaki, Simote Totauhelotu, et al.
Publicado: (2019)

Glial activation in prion diseases is selectively triggered by neuronal PrP(Sc)
por: Lakkaraju, Asvin K. K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9us9e2feo615k24dikvgs6cmbq