Potent antiviral agents fail to elicit genetically-stable resistance mutations in either enterovirus 71 or Coxsackievirus A16

Enterovirus 71 (EV71) and Coxsackievirus A16 (CVA16) are the two major causative agents of hand, foot and mouth disease (HFMD), for which there are currently no licenced treatments. Here, the acquisition of resistance towards two novel capsid-binding compounds, NLD and ALD, was studied and compared...

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Detalles Bibliográficos
Autores principales: Kelly, James T., De Colibus, Luigi, Elliott, Lauren, Fry, Elizabeth E., Stuart, David I., Rowlands, David J., Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678291/
https://www.ncbi.nlm.nih.gov/pubmed/26522770
http://dx.doi.org/10.1016/j.antiviral.2015.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678291/
https://www.ncbi.nlm.nih.gov/pubmed/26522770
http://dx.doi.org/10.1016/j.antiviral.2015.10.006

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