Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease

Hepatitis C virus (HCV) non-structural protein 2 (NS2) encodes an autoprotease activity that is essential for virus replication and thus represents an attractive anti-viral target. Recently, we demonstrated that a series of epoxide-based compounds, previously identified as potent inhibitors of the c...

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Detalles Bibliográficos
Autores principales: Shaw, Joseph, Harris, Mark, Fishwick, Colin W.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678293/
https://www.ncbi.nlm.nih.gov/pubmed/26518228
http://dx.doi.org/10.1016/j.antiviral.2015.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678293/
https://www.ncbi.nlm.nih.gov/pubmed/26518228
http://dx.doi.org/10.1016/j.antiviral.2015.10.001

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