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Successive site translocating inoculation potentiates DNA/recombinant vaccinia vaccination

DNA vaccines have advantages over traditional vaccine modalities; however the relatively low immunogenicity restrains its translation into clinical use. Further optimizations are needed to get the immunogenicity of DNA vaccine closer to the level required for human use. Here we show that intramuscul...

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Detalles Bibliográficos
Autores principales: Ren, Yanqin, Wang, Na, Hu, Weiguo, Zhang, Xiaoyan, Xu, Jianqing, Wan, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678304/
https://www.ncbi.nlm.nih.gov/pubmed/26667202
http://dx.doi.org/10.1038/srep18099