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Distinct promoter activation mechanisms modulate noise-driven HIV gene expression
Latent human immunodeficiency virus (HIV) infections occur when the virus occupies a transcriptionally silent but reversible state, presenting a major obstacle to cure. There is experimental evidence that random fluctuations in gene expression, when coupled to the strong positive feedback encoded by...
Autores principales: | Chavali, Arvind K., Wong, Victor C., Miller-Jensen, Kathryn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678399/ https://www.ncbi.nlm.nih.gov/pubmed/26666681 http://dx.doi.org/10.1038/srep17661 |
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