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Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells
BACKGROUND: Previously, we have demonstrated that human ABCB5 is a full-sized ATP-binding cassette transporter that shares strong homology with ABCB1/P-glycoprotein. ABCB5-transfected cells showed resistance to taxanes and anthracyclines. Herein, we further screened ABCB5 substrates, and explored th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678490/ https://www.ncbi.nlm.nih.gov/pubmed/26666373 http://dx.doi.org/10.1186/s40360-015-0038-5 |