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Spontaneous Formation of RNA Strands, Peptidyl RNA, and Cofactors
How the biochemical machinery evolved from simple precursors is an open question. Here we show that ribonucleotides and amino acids condense to peptidyl RNAs in the absence of enzymes under conditions established for genetic copying. Untemplated formation of RNA strands that can encode genetic infor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678511/ https://www.ncbi.nlm.nih.gov/pubmed/26435376 http://dx.doi.org/10.1002/anie.201506593 |