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CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1

BACKGROUND: CCR7 and MUC1 are correlated with lymph node metastasis in ESCC, but the role of MUC1 in the CCR7-induced lymphatic metastasis and the underlying molecular mechanism is still unclear. METHODS: The expression of CCR7 and MUC1 was detected in the ESCC samples by IHC, and the clinical signi...

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Detalles Bibliográficos
Autores principales: Shi, Mo, Chen, Dong, Yang, Dong, Liu, Xiang-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678529/
https://www.ncbi.nlm.nih.gov/pubmed/26667143
http://dx.doi.org/10.1186/s13046-015-0268-9