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The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer

Reliable mouse models are key in the discovery and development of novel anticancer treatments. Non-invasive monitoring techniques such as bioluminescence imaging (BLI) are useful tools to determine tumor engraftment and evaluate tumor growth. However, the development of ascites in ovarian cancer mou...

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Detalles Bibliográficos
Autores principales: Baert, Thaïs, Verschuere, Tina, Van Hoylandt, Anaïs, Gijsbers, Rik, Vergote, Ignace, Coosemans, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678634/
https://www.ncbi.nlm.nih.gov/pubmed/26676113
http://dx.doi.org/10.1186/s40425-015-0102-0