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Relationship between CK19 expression, deregulation of normal keratinocyte differentiation pattern and high risk-human papilloma virus infection in oral and oropharyngeal squamous cell carcinoma

BACKGROUND: Simple epithelial keratins appear early during embryonic development and are expressed in non-stratified, ductal and pseudo-stratified epithelial tissues. CK19, the lowest molecular weight keratin, is also expressed in basal layer of squamous epithelia of mucosal surfaces. Previous studi...

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Detalles Bibliográficos
Autores principales: Santoro, Angela, Pannone, Giuseppe, Ninivaggi, Rossella, Petruzzi, Massimo, Santarelli, Andrea, Russo, Giuseppe Maria, Lepore, Silvia, Pietrafesa, Michele, Laurenzana, Ilaria, Leonardi, Rosalia, Bucci, Paolo, Natalicchio, Maria Iole, Lucchese, Alberta, Papagerakis, Silvana, Bufo, Pantaleo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678638/
https://www.ncbi.nlm.nih.gov/pubmed/26672675
http://dx.doi.org/10.1186/s13027-015-0041-x