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CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system

BACKGROUND: Cell-mediated immunity is critical for clearance of central nervous system (CNS) infection with the encephalitic flavivirus, West Nile virus (WNV). Prior studies from our laboratory have shown that WNV-infected neurons express chemoattractants that mediate recruitment of antiviral leukoc...

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Detalles Bibliográficos
Autores principales: Durrant, Douglas M., Daniels, Brian P., Pasieka, TracyJo, Dorsey, Denise, Klein, Robyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678669/
https://www.ncbi.nlm.nih.gov/pubmed/26667390
http://dx.doi.org/10.1186/s12974-015-0447-9