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A simple method for identifying parameter correlations in partially observed linear dynamic models
BACKGROUND: Parameter estimation represents one of the most significant challenges in systems biology. This is because biological models commonly contain a large number of parameters among which there may be functional interrelationships, thus leading to the problem of non-identifiability. Although...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678707/ https://www.ncbi.nlm.nih.gov/pubmed/26666642 http://dx.doi.org/10.1186/s12918-015-0234-3 |